Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.53 |
| ▸ | SHBG | P04278 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367638 | 0.88 | CYP3A4 (0.67) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL1444719 | 0.88 | CYP3A4 (0.67) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL13981790 | 0.88 | CYP3A4 (0.67) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL29362131 | 0.85 | SMN1; SMN2 (0.69) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL1782727 | 0.82 | CYP19A1 (0.65) | CYP3A4LMNAMAPTMAPK1SERPINA6 | |
| SCHEMBL12604834 | 0.82 | CYP19A1 (0.65) | CYP3A4LMNAMAPTMAPK1SERPINA6 | |
| SCHEMBL1782726 | 0.82 | CYP19A1 (0.65) | CYP3A4LMNAMAPTMAPK1SERPINA6 | |
| SCHEMBL516592 | 0.82 | LMNA (0.78) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11204626 | 0.81 | ALDH1A1 (0.72) | CYP3A4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11239171 | 0.80 | CYP19A1 (0.70) | ALDH1A1ABCB11KDM4ENR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678919-A | A kind of preparation method of Methylprednisolone succinate impurity | 重庆华邦胜凯制药有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-109485686-B | Method for improving content of key intermediate 6 beta in methylprednisolone succinate impurity synthesis | 重庆华邦胜凯制药有限公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-109678919-B | Preparation method of methylprednisolone succinate impurity | 重庆华邦胜凯制药有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-109678919-A | A kind of preparation method of Methylprednisolone succinate impurity | 重庆华邦胜凯制药有限公司 | 2019-04-26 | — | — | CN | disclosed |