Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | PGR | P06401 | 2/20 | 0.67 |
| ▸ | AR | P10275 | 2/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.67 |
| ▸ | SHBG | P04278 | 2/20 | 0.67 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1444719 | 1.00 | CYP3A4 (0.67) | CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL13981790 | 1.00 | CYP3A4 (0.67) | CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL37618 | 0.89 | CYP3A4 (0.70) | CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL29362131 | 0.88 | SMN1; SMN2 (0.69) | CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL28292237 | 0.88 | CYP3A4 (0.53) | CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL11204626 | 0.86 | ALDH1A1 (0.72) | CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA | |
| SCHEMBL1782726 | 0.85 | CYP19A1 (0.65) | CYP3A4SERPINA6LMNAMAPTMAPK1 | |
| SCHEMBL12604834 | 0.85 | CYP19A1 (0.65) | CYP3A4SERPINA6LMNAMAPTMAPK1 | |
| SCHEMBL1782727 | 0.85 | CYP19A1 (0.65) | CYP3A4SERPINA6LMNAMAPTMAPK1 | |
| SCHEMBL11403213 | 0.85 | LMNA (0.51) | CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841778-B1 | METHOD FOR PREPARING MEDROGESTONE | ABBOTT PRODUCTS GMBH (DE) | 2012-03-14 | — | — | EP | disclosed |