SCHEMBL28292314

SCHEMBL28292314

C=CC1=C(OC)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.43
MAPT P10636 6/20 0.43
KDM4E B2RXH2 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
CDC25A P30304 2/20 0.43
CDC25B P30305 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
LMNA P02545 2/20 0.43
POLB P06746 2/20 0.43
HPGD P15428 2/20 0.43
MAP2K7 O14733 1/20 0.43
GMNN O75496 1/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
ALOX15 P16050 1/20 0.43
CYP2C19 P33261 1/20 0.43
THPO P40225 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16556951 0.79 TTR (0.38) ALDH1A1MAPTKDM4ESMN1; SMN2CDC25A
SCHEMBL7152778 0.77 ALDH1A1 (0.45) ALDH1A1MAPTKDM4ESMN1; SMN2CDC25B
SCHEMBL15289027 0.75 MAPT (0.63) ALDH1A1MAPTKDM4ESMN1; SMN2CDC25A
SCHEMBL20944785 0.74 LTA4H (0.44) ALDH1A1LMNAKMT2ACA1CA2
SCHEMBL24726902 0.71 ALDH1A1 (0.36) ALDH1A1CDC25ACDC25BTDP1TP53
SCHEMBL20944787 0.71 ALDH1A1 (0.36) ALDH1A1CDC25ACDC25BTDP1TP53
SCHEMBL18203497 0.69 ALDH1A1 (0.55) ALDH1A1MAPTKDM4ESMN1; SMN2CDC25A
Methoxymethane SCHEMBL29277822 0.67 ALDH1A1 (0.52) ALDH1A1KDM4ESMN1; SMN2TDP1LMNA
SCHEMBL21140993 0.67 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL3382872 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109749000-A Low temperature curable addition polymers from vinyl aryl cyclobutene-containing monomers and methods for making the same 罗门哈斯电子材料有限责任公司 2019-05-14 CN claimed
CN-109749000-A Low temperature curable addition polymers from vinyl aryl cyclobutene-containing monomers and methods for making the same 罗门哈斯电子材料有限责任公司 2019-05-14 CN disclosed