SCHEMBL28292427

SCHEMBL28292427

COC(=O)CC(=O)c1cc(Cl)ccc1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC5 P28715 3/20 0.63
FEN1 P39748 3/20 0.63
ALDH1A1 P00352 5/20 0.54
TP53 P04637 1/20 0.52
MAPT P10636 4/20 0.50
LMNA P02545 3/20 0.50
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
HPGD P15428 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C19 P33261 1/20 0.46
GAA P10253 1/20 0.45
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
PLA2G1B P04054 1/20 0.44
XBP1 P17861 1/20 0.44
ALOX12 P18054 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4372575 0.86 ERCC5 (0.63) ERCC5FEN1ALDH1A1MAPTHPGD
SCHEMBL5775638 0.85 ERCC5 (0.58) ERCC5FEN1ALDH1A1TP53MAPT
SCHEMBL28847068 0.81 ERCC5 (0.56) ERCC5FEN1ALDH1A1TP53MAPT
SCHEMBL9264240 0.80 ABL1 (0.45) ERCC5FEN1ALDH1A1MAPTLMNA
SCHEMBL13516377 0.80 FLT1 (0.52) ERCC5FEN1ALDH1A1MAPTLMNA
SCHEMBL21581972 0.79 ALDH1A1 (0.58) ALDH1A1LMNATAS1R3TAS1R1HPGD
SCHEMBL853580 0.79 ERCC5 (0.61) ERCC5FEN1ALDH1A1MAPTLMNA
SCHEMBL30335736 0.79 ERCC5 (0.61) ERCC5FEN1ALDH1A1MAPTLMNA
SCHEMBL4363906 0.78 ABL1 (0.62) ERCC5FEN1ALDH1A1TP53MAPT
SCHEMBL16770754 0.78 ERCC5 (0.61) ERCC5FEN1ALDH1A1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109648976-A A kind of co-extruding biaxial stretched PET/PPS laminated film and preparation method thereof 四川东方绝缘材料股份有限公司 2019-04-19 CN claimed
CN-109648976-A A kind of co-extruding biaxial stretched PET/PPS laminated film and preparation method thereof 四川东方绝缘材料股份有限公司 2019-04-19 CN disclosed