Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.56 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.54 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.54 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.54 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.54 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.54 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.54 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.54 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.54 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.54 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20250628 | 0.87 | ALDH1A1 (0.54) | ALDH1A1HPGDCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL16252980 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL20177367 | 0.83 | HPGD (0.50) | ALDH1A1HPGDCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL8002583 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HPGDCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL2491198 | 0.81 | HPGD (0.58) | HPGDCYP1A2GPR139LMNANPC1 | |
| SCHEMBL8001466 | 0.81 | ALDH1A1 (0.67) | ALDH1A1HPGDCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL8947103 | 0.80 | KMT2A (0.60) | CYP1A2CYP2C19CYP3A4NFKB1LMNA | |
| SCHEMBL7218397 | 0.80 | LMNA (0.67) | ALDH1A1HPGDCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL21203065 | 0.79 | GPR139 (0.61) | ALDH1A1HPGDCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL2562971 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HPGDCYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805237-B1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | JIANGSU CHUANGTE PHARMACEUTICAL TECH CO LTD (CN) | 2026-01-28 | — | — | EP | disclosed |
| CN-115785137-A | Synthesis and application of peptide borate compound | 江苏正大丰海制药有限公司 | 2023-03-14 | — | — | CN | disclosed |
| US-11542283-B2 | Synthesis of peptide borate ester compound and use thereof | JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| US-11542283-B2 | Synthesis of peptide borate ester compound and use thereof | JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| CN-112384519-B | Synthesis and application of peptide borate compound | 江苏正大丰海制药有限公司 | 2022-11-25 | — | — | CN | disclosed |
| US-20210214377-A1 | SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF | JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) | 2021-07-15 | — | — | US | disclosed |
| US-20210214377-A1 | SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF | JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) | 2021-07-15 | — | — | US | disclosed |
| EP-3805237-A1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) | 2021-04-14 | — | — | EP | disclosed |
| EP-3805237-A1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) | 2021-04-14 | — | — | EP | disclosed |
| CN-112384519-A | Synthesis and application of peptide borate compound | 江苏正大丰海制药有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-108794520-B | Synthesis method of boric acid citrate compounds including Eszolomide | 北京大学 | 2020-07-24 | — | — | CN | disclosed |
| CN-110540547-A | Synthesis and application of peptide borate compound | QIN YANRU | 2019-12-06 | — | — | CN | disclosed |
| WO-2019228299-A1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | 江苏正大丰海制药有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |
| WO-2019228299-A1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | 江苏正大丰海制药有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |
| CN-108794520-A | The synthetic method of boric acid citric acid ester type compound including Ai Shazuo meter | 北京大学 | 2018-11-13 | — | — | CN | disclosed |
| CN-106986884-A | A kind of efficient high-purity boron-containing compound preparation method | 成都贝斯凯瑞生物科技有限公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-106608883-A | Synthetic method of proteasome inhibitor MLN9708 | 北京大学 | 2017-05-03 | — | — | CN | disclosed |
| CN-106518902-A | Preparation process method for boron-containing compound | 成都贝斯凯瑞生物科技有限公司 | 2017-03-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214377-A1 | SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF | SEM1, VIP, PSMB11 | ALDH1A1 4592/4885HPGD 2888/4885CYP1A2 4739/4885 |
| US-11542283-B2 | Synthesis of peptide borate ester compound and use thereof | SEM1, VIP, PSMB11 | ALDH1A1 4592/4885HPGD 2888/4885CYP1A2 4739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.