Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | PNMT | P11086 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30612409 | 1.00 | AKR1C3 (0.45) | AKR1C3MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL17797589 | 0.94 | PNMT (0.47) | AKR1C3MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL30612412 | 0.92 | ACHE (0.44) | AKR1C3MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL1950958 | 0.91 | MEN1 (0.49) | MAPTRAB9AMEN1KMT2APNMT | |
| Hydrochloric Acid SCHEMBL7467008 | 0.90 | MEN1 (0.48) | MAPTRAB9AMEN1KMT2APNMT | |
| SCHEMBL17797705 | 0.89 | ALDH1A1 (0.48) | AKR1C3MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL17797682 | 0.88 | MEN1 (0.44) | MAPTALDH1A1SMN1; SMN2POLBRAB9A | |
| SCHEMBL29113503 | 0.87 | PNMT (0.47) | AKR1C3MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL30612413 | 0.87 | PNMT (0.47) | AKR1C3MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4764965 | 0.85 | HRH3 (0.50) | MAPTALDH1A1SMN1; SMN2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810111-B | Pyrazolopyrimidine compound, and preparation method and application thereof | 上海医药集团股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-109810111-A | A kind of pyrazolone miazines compound, preparation method and application | 上海医药集团股份有限公司 | 2019-05-28 | — | — | CN | disclosed |