Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2956896 | 0.78 | MAPT (0.64) | PDGFRBMEN1KMT2APDGFRAMAPT | |
| SCHEMBL15333384 | 0.78 | MAOB (0.59) | PDGFRBMEN1KMT2APDGFRAMAPT | |
| SCHEMBL17175790 | 0.76 | PDE10A (0.62) | PDGFRBMEN1KMT2APDGFRAMAPT | |
| SCHEMBL14380264 | 0.75 | RAB9A (0.71) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL1202543 | 0.75 | IMPDH2 (0.63) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL4725465 | 0.75 | PDGFRB (0.55) | PDGFRBMEN1KMT2APDGFRAMAPT | |
| SCHEMBL7713938 | 0.74 | AR (0.64) | PDGFRBMEN1KMT2APDGFRAMAPT | |
| Methylene Chloride SCHEMBL30760638 | 0.74 | MAPT (0.58) | PDGFRBMEN1KMT2APDGFRAMAPT | |
| SCHEMBL1902587 | 0.74 | MEN1 (1.00) | PDGFRBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8171583 | 0.74 | PDGFRB (1.00) | PDGFRBPDGFRAMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651333-A | A kind of 2- indol-3-yl-quinolines with anti-tumor activity and its preparation method and application | 五邑大学 | 2019-04-19 | — | — | CN | disclosed |