SCHEMBL28292550

SCHEMBL28292550

C=CCOc1ccccc1C=C.O=C1C(c2ccccc2)=C(c2ccccc2)C(c2ccccc2)=C1c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.49
HSD17B10 Q99714 2/20 0.49
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
NPC1 O15118 2/20 0.40
LIG1 P18858 1/20 0.40
ALDH1A1 P00352 3/20 0.40
POLB P06746 1/20 0.40
RECQL P46063 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2A6 P11509 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
PTPRC P08575 1/20 0.38
GAA P10253 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3659231 0.83 HPGD (0.66) HPGDHSD17B10TSHRMAPK1KMT2A
Trifluoromethanesulfonic Acid SCHEMBL27793822 0.74 HPGD (0.52) HPGDHSD17B10TSHRMAPK1KMT2A
SCHEMBL10947101 0.73 HPGD (0.62) HPGDHSD17B10TSHRMAPK1KMT2A
SCHEMBL5597152 0.73 ALDH1A1 (0.52) HPGDHSD17B10TSHRMAPK1KMT2A
SCHEMBL1482988 0.73 ALDH1A1 (0.68) HPGDHSD17B10TSHRMAPK1KMT2A
SCHEMBL29690311 0.73 ALDH1A1 (0.68) HPGDHSD17B10TSHRMAPK1KMT2A
SCHEMBL28291100 0.72 PDE4B (0.41) HPGDHSD17B10KMT2AMEN1NPC1
SCHEMBL28292552 0.70 PDE4B (0.45) HPGDKMT2AMEN1NPC1ALDH1A1
1,2-Diallyloxybenzene SCHEMBL29768784 0.70 HPGD (0.60) HPGDHSD17B10TSHRMAPK1LIG1
1,2-Diallyloxybenzene SCHEMBL366516 0.70 HPGD (0.60) HPGDHSD17B10TSHRMAPK1LIG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651564-A From the polymer and preparation method for passing through the cured monomer containing double arylcyclobutene groups of other groups 罗门哈斯电子材料有限责任公司 2019-04-19 CN disclosed