Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 4/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720510 | 0.87 | OPRK1 (0.45) | MEN1KMT2AOPRK1KCNH2ADORA3 | |
| SCHEMBL29262259 | 0.86 | MEN1 (0.48) | MEN1KMT2AOPRK1KCNH2RAF1 | |
| SCHEMBL28294351 | 0.82 | MEN1 (0.44) | MEN1KMT2ARAF1BRAFKDM4E | |
| SCHEMBL28292592 | 0.82 | KDR (0.53) | MEN1KMT2ARAF1MKNK2BRAF | |
| SCHEMBL28690607 | 0.82 | MEN1 (0.44) | MEN1KMT2AOPRK1KCNH2KDM4E | |
| SCHEMBL2624147 | 0.81 | KDM4E (0.54) | OPRK1KCNH2KDM4E | |
| SCHEMBL23488363 | 0.80 | PARP10 (0.55) | MEN1KMT2AOPRK1KCNH2KDM4E | |
| SCHEMBL4348844 | 0.80 | OPRK1 (0.41) | OPRK1KCNH2ADORA3TSHRMC4R | |
| SCHEMBL9572453 | 0.79 | MEN1 (0.53) | MEN1KMT2AMKNK1MKNK2KDM4E | |
| SCHEMBL28723866 | 0.79 | KMT2A (0.53) | MEN1KMT2AMKNK1MKNK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |