Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678768 | 0.82 | CCR1 (0.48) | KMT2AMAPTKDM4ETDP1NR3C2 | |
| SCHEMBL29262259 | 0.82 | MEN1 (0.48) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL28292634 | 0.82 | MEN1 (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL28292592 | 0.78 | KDR (0.53) | MEN1KMT2AKDR | |
| SCHEMBL28294351 | 0.78 | MEN1 (0.44) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL15880806 | 0.78 | CYP1A2 (0.50) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL168824 | 0.76 | P2RX3 (0.45) | P2RX3KDR | |
| SCHEMBL27913654 | 0.76 | ALDH1A1 (0.44) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL2642964 | 0.75 | ALDH1A1 (0.40) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL15880687 | 0.75 | KMT2A (0.52) | MEN1KMT2AKDM4EPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008025-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-02-01 | — | — | CN | disclosed |