Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394181 | 0.80 | KMT2A (0.54) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL12751389 | 0.77 | DYRK2 (0.51) | HTR2CALDH1A1HRH3HTR2APNMT | |
| SCHEMBL12751376 | 0.77 | HTR2C (0.45) | TDP1HTR2CTRIM24TRIM33DRD2 | |
| SCHEMBL12751382 | 0.77 | HTR2C (0.47) | LMNAHTR2CALDH1A1TSHRHRH3 | |
| SCHEMBL12751291 | 0.77 | IKBKB (0.51) | KMT2AHTR2CHRH3HTR2APNMT | |
| Hydrochloric Acid SCHEMBL1473505 | 0.76 | IKBKB (0.50) | KMT2AMEN1HTR2CHRH3HTR2A | |
| Hydrochloric Acid SCHEMBL7983894 | 0.76 | DYRK2 (0.50) | HTR2CALDH1A1HRH3HTR2APNMT | |
| Hydrochloric Acid SCHEMBL6979971 | 0.76 | IKBKB (0.50) | KMT2AHTR2CHRH3HTR2AHTR2B | |
| Ortho-Phthalaldehyde SCHEMBL7621085 | 0.75 | LMNA (0.59) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL5015224 | 0.73 | TNF (0.51) | HTR2CMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661392-A | For treating the mitochondrial inhibitors of proliferative disorder | 巴斯利尔药物国际股份公司 | 2019-04-19 | — | — | CN | disclosed |