Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14167559 | 0.87 | NOTUM (0.57) | AKR1C3LSSUSP2KMT2ANOTUM | |
| SCHEMBL16610843 | 0.82 | MAPT (0.66) | USP2KMT2AMAPTNPY5RALDH1A1 | |
| SCHEMBL16610840 | 0.82 | PDK2 (0.49) | USP2KMT2ANOTUMME3MAPT | |
| SCHEMBL14241715 | 0.82 | CYP46A1 (0.50) | AKR1C3LSSUSP2NOTUMNPY5R | |
| SCHEMBL9501600 | 0.81 | NOTUM (0.68) | AKR1C3USP2KMT2ANOTUMTDP1 | |
| SCHEMBL9500414 | 0.81 | NOTUM (0.68) | USP2KMT2ANOTUMME3MAPT | |
| SCHEMBL29175599 | 0.81 | NOTUM (0.73) | NOTUM | |
| Hydrochloric Acid SCHEMBL9499696 | 0.80 | NOTUM (0.66) | AKR1C3USP2KMT2ANOTUMTDP1 | |
| SCHEMBL578424 | 0.79 | ALDH1A1 (0.50) | AKR1C3LSSUSP2KMT2AMAPT | |
| SCHEMBL19297512 | 0.78 | GPR119 (0.50) | AKR1C3KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661392-A | For treating the mitochondrial inhibitors of proliferative disorder | 巴斯利尔药物国际股份公司 | 2019-04-19 | — | — | CN | disclosed |