Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 10/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.41 |
| ▸ | CPT2 | P23786 | 6/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30781994 | 0.90 | KDM5A (0.37) | CPT1APRMT5WDR77CDK5CDK5R1 | |
| SCHEMBL29504572 | 0.82 | PRMT5 (0.55) | CPT1APRMT5WDR77CPT2GRM5 | |
| SCHEMBL31430923 | 0.82 | PRMT5 (0.55) | CPT1APRMT5WDR77CPT2GRM5 | |
| SCHEMBL15645841 | 0.80 | CPT1A (0.40) | CPT1APRMT5WDR77CPT2CDK5 | |
| SCHEMBL28034186 | 0.78 | GSK3B (0.37) | KDM5A | |
| SCHEMBL38659451 | 0.77 | HSD11B1 (0.51) | CPT1APRMT5WDR77GRM5 | |
| SCHEMBL8296762 | 0.77 | HSD11B1 (0.51) | CPT1APRMT5WDR77GRM5 | |
| SCHEMBL1963995 | 0.75 | PRMT5 (0.39) | CPT1APRMT5WDR77CPT1BKDM5A | |
| SCHEMBL12090215 | 0.75 | CHRNB2 (0.51) | — | |
| SCHEMBL30297700 | 0.74 | GRM5 (0.42) | CPT1APRMT5WDR77CPT2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661392-A | For treating the mitochondrial inhibitors of proliferative disorder | 巴斯利尔药物国际股份公司 | 2019-04-19 | — | — | CN | disclosed |