Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 9/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | CPT2 | P23786 | 5/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292819 | 0.80 | CPT1A (0.42) | CPT1APRMT5WDR77CPT2CDK5 | |
| SCHEMBL12090215 | 0.72 | CHRNB2 (0.51) | KDM4EALDH1A1LMNA | |
| SCHEMBL23853485 | 0.70 | MAP4K4 (0.39) | CPT1ACPT2KDM5AGRM5PRCP | |
| SCHEMBL30781994 | 0.70 | KDM5A (0.37) | CPT1APRMT5WDR77GPR119CDK5 | |
| SCHEMBL15645839 | 0.69 | GPR119 (0.35) | CPT1APRMT5WDR77CPT2GPR119 | |
| SCHEMBL25063295 | 0.69 | ALDH1A1 (0.41) | KDM4EALDH1A1LMNA | |
| SCHEMBL29491244 | 0.68 | PRMT5 (0.55) | CPT1APRMT5WDR77HSD11B1GPR119 | |
| SCHEMBL28814072 | 0.68 | PRMT5 (0.55) | CPT1APRMT5WDR77HSD11B1GPR119 | |
| SCHEMBL29021048 | 0.68 | GPR119 (0.49) | HSD11B1GPR119KDM4EALDH1A1LMNA | |
| SCHEMBL12090398 | 0.68 | CHRNA7 (0.50) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014062938-A1 | RORY MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-04-24 | — | — | WO | disclosed |