SCHEMBL28292946

SCHEMBL28292946

CC(Br)c1ccccc1-c1ccc(O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 2/20 0.47
ABCB1 P08183 2/20 0.47
BCR P11274 2/20 0.47
PTPN1 P18031 1/20 0.43
BACE1 P56817 1/20 0.43
ESR2 Q92731 5/20 0.43
MMP3 P08254 1/20 0.41
BCL2L1 Q07817 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
ESR1 P03372 4/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
RPS6KA3 P51812 1/20 0.37
PDE4A P27815 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1513629 0.84 CA1 (0.56) ABL1ABCB1BCRPTPN1BACE1
SCHEMBL3264500 0.84 ABL1 (0.50) ABL1ABCB1BCRPTPN1BACE1
SCHEMBL4588816 0.84 ALDH1A1 (0.44) PTPN1BACE1BCL2L1CA12CA1
SCHEMBL9513577 0.82 ABL1 (0.48) ABL1ABCB1BCRPTPN1BACE1
SCHEMBL1758175 0.79 ABL1 (0.54) ABL1ABCB1BCRPTPN1BACE1
SCHEMBL28114560 0.78 TSHR (0.58) ABL1ABCB1BCRPTPN1BACE1
SCHEMBL8148942 0.77 PTGS2 (0.51) ABL1ABCB1BCRPTPN1MMP3
Oxirane SCHEMBL28242449 0.77 CA1 (0.49) ABL1ABCB1BCRPTPN1BACE1
Cyanate SCHEMBL27635992 0.77 ESR2 (0.51) ABL1ABCB1BCRPTPN1BACE1
SCHEMBL28743249 0.76 ABL1 (0.46) ABL1ABCB1BCRPTPN1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109825312-A Liquid crystal media with vertical plane orientation 默克专利股份有限公司 2019-05-31 CN disclosed