Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | PTPRB | P23467 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293151 | 1.00 | ALDH1A1 (0.35) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL28245452 | 0.88 | PTPRB (0.34) | ALDH1A1KMT2APTPRBCCR2LTA4H | |
| SCHEMBL500280 | 0.77 | PTPRB (0.44) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL500279 | 0.77 | PTPRB (0.44) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL29794289 | 0.77 | PTPRB (0.44) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL1709804 | 0.71 | MAPT (0.47) | ALDH1A1MAPTMEN1KMT2AHTT | |
| Ammonia Solution, Strong SCHEMBL19894166 | 0.70 | ADORA2A (0.35) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL683494 | 0.68 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL17429753 | 0.68 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2APOLB | |
| Bromide SCHEMBL17419382 | 0.67 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2APTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109771421-A | The method for treating vascular leak syndrome | 爱尔皮奥治疗有限公司 | 2019-05-21 | — | — | CN | disclosed |