Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044824 | 0.76 | HCAR3 (0.43) | HCAR3TRPM8PDE10A | |
| SCHEMBL15382065 | 0.76 | HCAR3 (0.43) | HCAR3TRPM8EDNRAALDH1A1SMN1; SMN2 | |
| SCHEMBL15718387 | 0.75 | — | — | |
| SCHEMBL30206305 | 0.75 | — | — | |
| SCHEMBL26866959 | 0.74 | HCAR3 (0.42) | HCAR3TRPM8PDE10A | |
| SCHEMBL26614830 | 0.74 | GPR55 (0.52) | — | |
| SCHEMBL26614828 | 0.74 | GPR55 (0.52) | — | |
| SCHEMBL18053163 | 0.74 | CHEK1 (0.45) | HCAR3MAPKAPK2CDK2 | |
| Hydrochloric Acid SCHEMBL28583898 | 0.73 | NNMT (0.39) | HCAR3EDNRASIRT6 | |
| SCHEMBL15781883 | 0.72 | HCAR3 (0.44) | HCAR3TRPM8GAATDP1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103421-B | The pyrazine regulator of GPR6 | 武田药品工业株式会社 | 2019-04-09 | — | — | CN | disclosed |