Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24826336 | 1.00 | LMNA (0.37) | LMNACTSKSLC6A3ALDH1A1GAA | |
| SCHEMBL18893472 | 1.00 | LMNA (0.37) | LMNACTSKSLC6A3ALDH1A1GAA | |
| SCHEMBL18937936 | 1.00 | LMNA (0.37) | LMNACTSKSLC6A3ALDH1A1GAA | |
| SCHEMBL24919515 | 1.00 | LMNA (0.37) | LMNACTSKSLC6A3ALDH1A1GAA | |
| SCHEMBL18935670 | 1.00 | LMNA (0.37) | LMNACTSKSLC6A3ALDH1A1GAA | |
| SCHEMBL18893329 | 0.94 | LMNA (0.35) | LMNACTSKSLC6A3ALDH1A1GAA | |
| SCHEMBL7439199 | 0.77 | KCNH2 (0.47) | LMNACTSKSLC6A3ALDH1A1GAA | |
| SCHEMBL27769538 | 0.77 | CTSK (0.39) | LMNACTSKSLC6A3ALDH1A1GAA | |
| SCHEMBL27769548 | 0.77 | CTSK (0.39) | LMNACTSKSLC6A3ALDH1A1GAA | |
| SCHEMBL27769588 | 0.77 | CTSK (0.39) | LMNACTSKSLC6A3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790079-B | C (sp) of organozinc reagents and heterocyclic (pseudo) halides3)-C(sp2) Cross-coupling reaction | 香港科技大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-109790079-A | C (the sp of organic zinc reagent and heterocycle (quasi-) halide3)-C(sp2) cross-coupling reaction | 香港科技大学 | 2019-05-21 | — | — | CN | disclosed |