Pyridine

Pyridine

SCHEMBL28293453

NC(=O)NNc1cccc(Cl)c1.c1ccncc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.56
GAA P10253 5/20 0.56
ALDH1A1 P00352 4/20 0.56
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
GFER P55789 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.51
POLB P06746 1/20 0.50
GRM4 Q14833 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
NPC1 O15118 4/20 0.46
LMNA P02545 3/20 0.46
RAB9A P51151 3/20 0.46
HTT P42858 2/20 0.46
HTR3E A5X5Y0 1/20 0.46
HTR3B O95264 1/20 0.46
HTR3A P46098 1/20 0.46
HTR3D Q70Z44 1/20 0.46
HTR3C Q8WXA8 1/20 0.46
KDR P35968 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7585259 0.89 MAPT (0.69) MAPTGAAALDH1A1MEN1KMT2A
Pyridine SCHEMBL28295246 0.83 PTGS2 (0.53) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL2137703 0.77 MAPT (0.61) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL20984323 0.76 MAPT (0.62) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL28871718 0.73 GRM4 (0.76) MAPTGAAALDH1A1GFERSMN1; SMN2
3-Chloroaniline SCHEMBL28293455 0.73 ALDH1A1 (0.59) MAPTALDH1A1MEN1KMT2AGFER
Pyridine SCHEMBL28295244 0.73 POLB (0.48) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL9690067 0.73 GAA (1.00) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL167193 0.72 MEN1 (0.71) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL26105067 0.72 ALDH1A1 (0.53) MAPTGAAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107216411-B One kind quaternary ammonium salt of Acetylated Chitosans containing ureas and its preparation method and application 中国科学院烟台海岸带研究所 2019-06-11 CN disclosed