Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | GAA | P10253 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.54 |
| ▸ | HTR3B | O95264 | 2/20 | 0.54 |
| ▸ | HTR3A | P46098 | 2/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28293453 | 0.89 | MAPT (0.56) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL20984323 | 0.85 | MAPT (0.62) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL2137703 | 0.83 | MAPT (0.61) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9690067 | 0.81 | GAA (1.00) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL167193 | 0.81 | MEN1 (0.71) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL26105067 | 0.81 | ALDH1A1 (0.53) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL5691420 | 0.79 | DDX3X (0.58) | MAPTGAAALDH1A1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28790660 | 0.79 | MEN1 (0.69) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL2139137 | 0.79 | MAPT (0.56) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL22091065 | 0.78 | GAA (0.49) | GAAALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797098-B1 | Method for stabilizing bilirubin in control sera and calibrators | ROCHE DIAGNOSTICS GMBH (DE) | 2002-10-02 | — | — | EP | disclosed |
| US-5854073-A | Stabilization of bilirubin in control sera and calibrators | BOHRINGER MANNHEIM GMBH (DE) | 1998-12-29 | — | — | US | disclosed |
| EP-0797098-A2 | Method for stabilizing bilirubin in control sera and calibrators | Roche Diagnostics GmbH (DE) | 1997-09-24 | — | — | EP | disclosed |
| US-5196314-A | Colorimetric, tetrazole compunds to reduce interference | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-23 | — | — | US | disclosed |
| EP-0239931-B1 | PROCESS AND REAGENT FOR THE DETERMINATION OF SUBSTRATES OR ENZYME ACTIVITIES | Roche Diagnostics GmbH (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-5013647-A | Determination of enzyme substrate or enzyme activity, uric acid, creatinine | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-07 | — | — | US | disclosed |
| EP-0239931-A2 | Process and reagent for the determination of substrates or enzyme activities | Roche Diagnostics GmbH (DE) | 1987-10-07 | — | — | EP | disclosed |
| EP-0161436-B1 | REDOX INDICATORS | Roche Diagnostics GmbH (DE) | 1987-09-02 | — | — | EP | disclosed |
| US-4665023-A | MEDICAL DIAGNOSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1987-05-12 | — | — | US | disclosed |
| EP-0161436-A1 | Redox indicators | Roche Diagnostics GmbH (DE) | 1985-11-21 | — | — | EP | disclosed |
| US-4297271-A | CHROMAGEN IN A DIAGNOSTIC TEST FOR FECAL BLOOD; CHROMATOGRAPHY | BOEHRINGER MANNHEIM GMBH (DE) | 1981-10-27 | — | — | US | disclosed |
| US-4219336-A | HYDROGEN PEROXIDE, GUAIACONIC ACID | BOEHRINGER MANNHEIM GMBH (DE) | 1980-08-26 | — | — | US | disclosed |