Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 8/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22291523 | 0.83 | CHRM2 (0.45) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL29025239 | 0.83 | CHRNB2 (0.43) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL7765958 | 0.80 | — | — | |
| SCHEMBL8239944 | 0.78 | CHRNB2 (0.48) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL17399540 | 0.78 | CHRNB2 (0.52) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL1766714 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL8108272 | 0.76 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| Trimethylammonium SCHEMBL11601657 | 0.76 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL16244292 | 0.76 | LMNA (0.42) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL7769338 | 0.76 | LMNA (0.42) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790152-A | The diagnosis of neurotensin receptor associated disease treats and prevents | 埃朗根-纽伦堡 弗里德里希-亚历山大大学 | 2019-05-21 | — | — | CN | disclosed |