Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28183477 | 0.79 | KDM4E (0.31) | — | |
| SCHEMBL19064597 | 0.78 | EGFR (0.35) | EGFR | |
| SCHEMBL3473060 | 0.74 | MEN1 (0.45) | EGFR | |
| SCHEMBL15540429 | 0.74 | CYP1A2 (0.36) | EGFR | |
| SCHEMBL31285235 | 0.72 | CES2 (0.38) | EGFR | |
| SCHEMBL2783567 | 0.72 | CES2 (0.38) | EGFR | |
| SCHEMBL28097638 | 0.72 | CES2 (0.38) | EGFR | |
| SCHEMBL29904968 | 0.70 | EGFR (0.34) | EGFR | |
| SCHEMBL28428263 | 0.70 | SLC40A1 (0.49) | — | |
| SCHEMBL27041012 | 0.70 | EGFR (0.34) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790122-A | Heterocyclic compound | 武田药品工业株式会社 | 2019-05-21 | — | — | CN | disclosed |