Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595736 | 0.78 | SLC40A1 (0.61) | SLC40A1PKMPTGES2CA1CA2 | |
| SCHEMBL22145982 | 0.77 | SLC40A1 (0.59) | SLC40A1PKMPTGES2CA1CA2 | |
| SCHEMBL16263833 | 0.76 | SLC40A1 (0.52) | SLC40A1PKMEIF2AK3PTGES2CA1 | |
| SCHEMBL21442625 | 0.76 | SLC40A1 (0.52) | SLC40A1PKMEIF2AK3PTGES2CA1 | |
| SCHEMBL26339156 | 0.75 | BDKRB1 (0.50) | SLC40A1PKMEIF2AK3PTGES2BRD4 | |
| SCHEMBL28422673 | 0.74 | SLC40A1 (0.50) | SLC40A1PKMEIF2AK3PTGES2CA1 | |
| SCHEMBL14717351 | 0.73 | FABP4 (0.54) | SLC40A1PKMCCKBR | |
| SCHEMBL28422630 | 0.73 | SLC40A1 (0.49) | SLC40A1PKMEIF2AK3PTGES2CA1 | |
| SCHEMBL3026118 | 0.72 | EIF2AK3 (0.48) | SLC40A1PKMEIF2AK3PTGES2CA1 | |
| SCHEMBL22234291 | 0.70 | KEAP1 (0.59) | SLC40A1PKMPTGES2BRD4CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829613-B | Diaryl-substituted pyrazolo ring derivative, preparation method thereof and application thereof in medical field | 赤峰蒙广生物科技有限公司 | 2020-06-09 | — | — | CN | disclosed |