Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261175 | 0.81 | CHKA (0.51) | CHKAKCNMA1MEN1KMT2A | |
| SCHEMBL8685760 | 0.81 | GRIK1 (0.48) | CHKAGRM5KCNMA1PYGLMEN1 | |
| SCHEMBL3409401 | 0.73 | KCNA5 (0.49) | GRM5KCNA5 | |
| Hydrochloric Acid SCHEMBL4024971 | 0.71 | KCNA5 (0.47) | GRM5KCNA5 | |
| SCHEMBL6732495 | 0.70 | ALDH1A1 (0.53) | GRM5NPC1CYP19A1CYP11B2KCNA5 | |
| SCHEMBL3222106 | 0.69 | HSD17B10 (0.50) | NPC1MEN1KMT2A | |
| SCHEMBL6730575 | 0.69 | NPC1 (0.54) | GRM5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3553376 | 0.69 | GRM5 (0.40) | GRM5PYGLKCNA5 | |
| SCHEMBL913751 | 0.69 | MKNK1 (0.44) | GRM5 | |
| SCHEMBL10814850 | 0.69 | HSP90AA1 (0.48) | GRM5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104045552-B | Medicinal compound as neuroprotective agent | 江苏先声药业有限公司 | 2019-06-11 | — | — | CN | disclosed |