Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1717658 | 0.82 | F2 (0.49) | MMP2MMP9BCHEACHEMMP14 | |
| SCHEMBL17942299 | 0.81 | NAMPT (0.53) | MMP2MMP9BCHEACHEMMP14 | |
| Hydrochloric Acid SCHEMBL4919354 | 0.81 | F2 (0.50) | MMP2MMP9BCHEACHEMMP14 | |
| SCHEMBL1718743 | 0.80 | TP53 (0.46) | MAPTMMP2MMP9BCHEACHE | |
| SCHEMBL10976389 | 0.79 | BCHE (0.49) | CNR2MMP2MMP9BCHEACHE | |
| SCHEMBL5518065 | 0.78 | KEAP1 (0.65) | MMP2MMP9MMP14TSHRKEAP1 | |
| SCHEMBL10983944 | 0.78 | HTR6 (0.54) | CNR2NR3C1MMP2MMP9BCHE | |
| Benzylsulfonylbenzene SCHEMBL780337 | 0.76 | TSHR (0.68) | MAPTMMP2MMP9TSHRHSD17B10 | |
| SCHEMBL3237305 | 0.76 | KEAP1 (0.46) | CNR2NR3C1MMP2MMP9BCHE | |
| SCHEMBL19857239 | 0.76 | KIF11 (0.54) | MMP2MMP9BCHEACHEMMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761863-B | (E) - (2- (phenylsulfonyl) ethenyl) benzene and its derivative and synthetic method | 湘潭大学 | 2020-10-02 | — | — | CN | claimed |
| CN-109761863-B | (E) - (2- (phenylsulfonyl) ethenyl) benzene and its derivative and synthetic method | 湘潭大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-109761863-A | (E)-(2-(phenyl sulfonyl) vinyl) benzene and its derivative and synthetic method | 湘潭大学 | 2019-05-17 | — | — | CN | disclosed |