Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28467941 | 0.93 | TSHR (0.57) | HSD11B1MAPTKIF11KMT2ATSHR | |
| SCHEMBL28110722 | 0.86 | MAPT (0.53) | HSD11B1MAPTKIF11KMT2ATSHR | |
| SCHEMBL16886402 | 0.83 | MAPT (0.50) | HSD11B1MAPTKMT2ATSHRHSD17B10 | |
| SCHEMBL6723028 | 0.83 | NR1H3 (0.60) | MAPTTSHRHSD17B10ALDH1A1 | |
| SCHEMBL14601736 | 0.83 | KIF11 (0.50) | KIF11KMT2APTGDR2PPARGMMP1 | |
| SCHEMBL5010591 | 0.83 | KIF11 (0.50) | HSD11B1KIF11KMT2ATSHRHSD17B10 | |
| SCHEMBL17943805 | 0.81 | HSD11B1 (0.66) | HSD11B1MAPT | |
| SCHEMBL28279320 | 0.81 | MAPT (0.48) | HSD11B1MAPTKIF11KMT2ATSHR | |
| Benzylsulfonylbenzene SCHEMBL780337 | 0.80 | TSHR (0.68) | MAPTKMT2ATSHRHSD17B10ALDH1A1 | |
| SCHEMBL776229 | 0.79 | MAPT (0.61) | HSD11B1MAPTKMT2ATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761863-B | (E) - (2- (phenylsulfonyl) ethenyl) benzene and its derivative and synthetic method | 湘潭大学 | 2020-10-02 | — | — | CN | claimed |
| CN-109761863-A | (E)-(2-(phenyl sulfonyl) vinyl) benzene and its derivative and synthetic method | 湘潭大学 | 2019-05-17 | — | — | CN | claimed |
| CN-109761863-B | (E) - (2- (phenylsulfonyl) ethenyl) benzene and its derivative and synthetic method | 湘潭大学 | 2020-10-02 | — | — | CN | disclosed |