SCHEMBL5010591

SCHEMBL5010591

O=S(=O)(Cc1ccc(C(F)(F)F)cc1)c1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.49
CHEK1 O14757 1/20 0.48
AURKA O14965 1/20 0.48
NTRK1 P04629 1/20 0.48
MET P08581 1/20 0.48
PIM1 P11309 1/20 0.48
FGFR1 P11362 1/20 0.48
PRKACA P17612 1/20 0.48
GRK5 P34947 1/20 0.48
MAP2K2 P36507 1/20 0.48
FLT3 P36888 1/20 0.48
MAPK8 P45983 1/20 0.48
MAPK9 P45984 1/20 0.48
CDK8 P49336 1/20 0.48
GSK3B P49841 1/20 0.48
CDK7 P50613 1/20 0.48
CDK9 P50750 1/20 0.48
RPS6KA3 P51812 1/20 0.48
LIMK1 P53667 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11048869 0.86 CA2 (0.55) KMT2ACA2TSHRHSD17B10
SCHEMBL21510835 0.86 CA2 (0.55) KMT2ACA2TSHRHSD17B10
SCHEMBL14601736 0.83 KIF11 (0.50) KIF11PTGDR2MMP1KMT2ABCHE
SCHEMBL28293662 0.83 HSD11B1 (0.58) KIF11PTGDR2MMP1KMT2AHSD11B1
SCHEMBL28467941 0.83 TSHR (0.57) KIF11PTGDR2MMP1KMT2AHSD11B1
SCHEMBL2922447 0.81 POLB (0.49) MMP1KMT2AMTORCA2TSHR
SCHEMBL29007566 0.80 BMP1 (0.52) KIF11PTGDR2KMT2AHSD11B1
SCHEMBL7940681 0.78 KIF11 (0.59) KIF11CHEK1AURKANTRK1MET
SCHEMBL28887988 0.77 MAPT (0.57) KMT2ACA2ACHETSHRHSD17B10
SCHEMBL5002569 0.77 MAPT (0.57) KMT2ACA2ACHETSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1589020-B1 NOVEL COMPOUNDS CAPABLE OF FORMING PHOTOCONVERTIBLE ORGANIC THIN FILMS AND ARTICLES HAVING ORGANIC THIN FILMS NIPPON SODA CO (JP) 2013-06-05 EP disclosed
US-7470803-B2 Compounds for forming photoconvertible organic thin film and organic thin film formed body NIPPON SODA CO., LTD. (JP) 2008-12-30 US disclosed
US-20060138400-A1 Novel compounds capable of forming photoconvertible organic thin film and articles having organic thin film NIPPON SODA CO.,LTD. (JP) 2006-06-29 US disclosed
EP-1589020-A1 NOVEL COMPOUNDS CAPABLE OF FORMING PHOTOCONVERTIBLE ORGANIC THIN FILMS AND ARTICLES HAVING ORGANIC THIN FILMS NIPPON SODA CO., LTD. (JP) 2005-10-26 EP disclosed