Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326518 | 0.86 | KDM4E (0.58) | L3MBTL1ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL6366230 | 0.85 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL6366231 | 0.85 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL18890099 | 0.83 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL28293753 | 0.81 | MMP8 (0.50) | ALDH1A1TSHRKDM4E | |
| SCHEMBL1433326 | 0.80 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL10958923 | 0.79 | KDM4E (0.56) | L3MBTL1TDP1MTNR1BMTNR1AKDM4E | |
| SCHEMBL3918115 | 0.79 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL512066 | 0.78 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL11082984 | 0.78 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678902-A | One kind has the organic catalyst, ligand and synthesis and application of rigid spiral shell [indane -1,2 '-pyrrolidines] skeleton | 北京师范大学 | 2019-04-26 | — | — | CN | disclosed |