SCHEMBL28293765

SCHEMBL28293765

CCN(C)C=Nc1cc(C)c(Cc2cccc(C#N)c2)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.37
HRH3 Q9Y5N1 1/20 0.36
S1PR1 P21453 2/20 0.35
GLA P06280 1/20 0.34
SCN8A Q9UQD0 1/20 0.34
CYP19A1 P11511 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
MEP1A Q16819 1/20 0.32
MEP1B Q16820 1/20 0.32
CA1 P00915 1/20 0.32
KMT2A Q03164 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
MPO P05164 1/20 0.31
KLKB1 P03952 1/20 0.31
GRIA2 P42262 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28293764 0.87 CYP2A6 (0.37) IDH1HRH3CYP19A1CYP11B1CYP11B2
SCHEMBL28292092 0.83 HDAC1 (0.37) KMT2A
SCHEMBL28292068 0.83 TAAR1 (0.39) KMT2A
SCHEMBL28292062 0.82 CHRM4 (0.37) IDH1
SCHEMBL28292069 0.82
SCHEMBL28292058 0.82 TAAR1 (0.38)
SCHEMBL27201095 0.80 IDH1 (0.36) IDH1HRH3S1PR1GLASCN8A
SCHEMBL28872646 0.79 ALDH1A1 (0.38)
SCHEMBL28293867 0.78 TSHR (0.33) CYP19A1KMT2ASLC6A2SLC6A4SLC6A3
SCHEMBL22232360 0.77 IDH1 (0.36) IDH1HRH3S1PR1GLASCN8A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843056-A 4-substituted phenylamine derivatives and their use for protecting crops against undesired phytopathogenic microorganisms 印度商皮埃企业有限公司 2019-06-04 CN claimed
CN-109843056-A 4-substituted phenylamine derivatives and their use for protecting crops against undesired phytopathogenic microorganisms 印度商皮埃企业有限公司 2019-06-04 CN disclosed