SCHEMBL28293764

SCHEMBL28293764

CCN(C)C=Nc1cc(C)c(Cc2ccc(C#N)cc2)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.37
ALDH1A1 P00352 3/20 0.36
LOXL2 Q9Y4K0 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
AR P10275 2/20 0.34
IDH1 O75874 1/20 0.34
HRH3 Q9Y5N1 4/20 0.33
TSHR P16473 2/20 0.33
RECQL P46063 1/20 0.33
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
NSD2 O96028 1/20 0.31
SAE1 Q9UBE0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28293765 0.87 IDH1 (0.37) KMT2AIDH1HRH3CYP19A1CYP11B1
SCHEMBL28293773 0.83 ENPP1 (0.33) KMT2A
SCHEMBL28293884 0.83 KDM4E (0.33) ALDH1A1KDM4E
SCHEMBL28292062 0.83 CHRM4 (0.37) ALDH1A1KDM4EHPGDIDH1TSHR
SCHEMBL28872646 0.82 ALDH1A1 (0.38) ALDH1A1MAPT
SCHEMBL28293755 0.79 ALDH1A1 (0.32) ALDH1A1
SCHEMBL28292063 0.79 RIPK1 (0.30)
SCHEMBL28292035 0.79 KMT2A (0.42) ALDH1A1MEN1MAPTHPGDKMT2A
SCHEMBL28293867 0.78 TSHR (0.33) ALDH1A1MEN1MAPTKMT2ATSHR
SCHEMBL27201073 0.78 CYP2A6 (0.36) CYP2A6ALDH1A1LOXL2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843056-A 4-substituted phenylamine derivatives and their use for protecting crops against undesired phytopathogenic microorganisms 印度商皮埃企业有限公司 2019-06-04 CN claimed
CN-109843056-A 4-substituted phenylamine derivatives and their use for protecting crops against undesired phytopathogenic microorganisms 印度商皮埃企业有限公司 2019-06-04 CN disclosed