Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12290803 | 0.81 | KDM4E (0.39) | CHRNB2CHRNA4KDM4EHDAC4HDAC2 | |
| SCHEMBL16959151 | 0.81 | CHRNB2 (0.36) | CHRNB2CHRNA4KDM4EHDAC4HDAC2 | |
| SCHEMBL16954530 | 0.77 | — | — | |
| SCHEMBL16951923 | 0.77 | — | — | |
| SCHEMBL16953383 | 0.77 | BRD4 (0.30) | — | |
| SCHEMBL16236038 | 0.74 | NPC1 (0.39) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL12290448 | 0.74 | TSHR (0.48) | CHRNB2CHRNA4KDM4EHDAC4HDAC2 | |
| SCHEMBL1808224 | 0.72 | ALDH1A1 (0.55) | KDM4EADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL16955089 | 0.72 | — | — | |
| SCHEMBL28045418 | 0.71 | MAOA (0.37) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734686-B | Catalytic synthesis method of 2-substituted benzofuran compound | 浙江万里学院 | 2022-07-01 | — | — | CN | claimed |
| CN-109734686-B | Catalytic synthesis method of 2-substituted benzofuran compound | 浙江万里学院 | 2022-07-01 | — | — | CN | disclosed |
| CN-109734686-A | A kind of 2- replaces the process for catalytic synthesis of benzofuran compounds | 浙江万里学院 | 2019-05-10 | — | — | CN | disclosed |