⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27624078 | 0.76 | HPGD (0.36) | — | |
| SCHEMBL4659111 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL1416350 | 0.67 | — | — | |
| SCHEMBL27676677 | 0.66 | — | — | |
| Sulfuric Acid SCHEMBL4277252 | 0.65 | GAA (0.30) | — | |
| Hydrochloric Acid SCHEMBL26933944 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL28230827 | 0.64 | — | — | |
| SCHEMBL2154177 | 0.63 | HSD17B10 (0.39) | — | |
| SCHEMBL27673212 | 0.62 | TSHR (0.59) | — | |
| SCHEMBL8540432 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109925312-A | For treating the composition, preparation and method of eye disease | 爱尔皮奥治疗有限公司 | 2019-06-25 | — | — | CN | disclosed |
| CN-105307498-B | Compositions, formulations and methods for treating ocular diseases | 爱尔皮奥治疗有限公司 | 2019-04-16 | — | — | CN | disclosed |