Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010837 | 0.77 | AR (0.46) | ARGABRA1GABRG2GABRB3HTR3E | |
| SCHEMBL11205547 | 0.71 | AR (0.43) | ARRAB9AHSD17B1HSD17B2CYP3A4 | |
| SCHEMBL27948099 | 0.71 | NPC1 (0.48) | NPC1RAB9ASLC18A3SIGMAR1NOTUM | |
| SCHEMBL7915311 | 0.70 | HSD17B1 (0.61) | ARHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL3907230 | 0.69 | AR (0.44) | ARGABRA1GABRG2GABRB3NPC1 | |
| SCHEMBL15757454 | 0.68 | NPC1 (0.70) | NPC1RAB9ASLC18A3SIGMAR1GRIN2B | |
| SCHEMBL28560812 | 0.67 | AR (0.43) | ARHTR3EHTR3BCHRNA7HTR3A | |
| SCHEMBL72613 | 0.67 | AR (0.43) | ARNPC1RAB9AHSD17B1HSD17B2 | |
| SCHEMBL4489979 | 0.67 | MAOA (0.48) | ARNPC1RAB9AHSD17B1HSD17B2 | |
| SCHEMBL4947340 | 0.67 | CNR1 (0.50) | ARNPC1RAB9AHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109925312-A | For treating the composition, preparation and method of eye disease | 爱尔皮奥治疗有限公司 | 2019-06-25 | — | — | CN | disclosed |
| CN-105307498-B | Compositions, formulations and methods for treating ocular diseases | 爱尔皮奥治疗有限公司 | 2019-04-16 | — | — | CN | disclosed |