SCHEMBL28293841

SCHEMBL28293841

Cc1cc(Cc2ccc(Cl)cc2)c(C)cc1N

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
CYP3A4 P08684 3/20 0.47
CYP1A2 P05177 1/20 0.47
ALOX15 P16050 1/20 0.47
CASP7 P55210 1/20 0.47
HIF1A Q16665 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 1/20 0.42
LDHA P00338 1/20 0.42
LDHB P07195 1/20 0.42
NPC1 O15118 1/20 0.41
ATM Q13315 1/20 0.41
HSP90AB1 P08238 1/20 0.41
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
MPO P05164 1/20 0.40
ADCY10 Q96PN6 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28292124 0.84 ALDH1A1 (0.64) ALDH1A1CYP3A4CYP1A2ALOX15CASP7
SCHEMBL28292196 0.81 ALDH1A1 (0.56) ALDH1A1CYP3A4CYP1A2ALOX15CASP7
SCHEMBL26228621 0.79 ALDH1A1 (0.58) ALDH1A1CYP3A4CYP1A2ALOX15CASP7
SCHEMBL28352675 0.79 ALDH1A1 (0.62) ALDH1A1CYP3A4CYP1A2ALOX15CASP7
SCHEMBL941288 0.78 ALDH1A1 (1.00) ALDH1A1CYP3A4CYP1A2ALOX15CASP7
SCHEMBL21084580 0.78 CYP3A4 (0.53) ALDH1A1CYP3A4ALOX15HIF1AHSD17B10
SCHEMBL23926305 0.77 ALDH1A1 (0.55) ALDH1A1CYP3A4CYP1A2ALOX15CASP7
SCHEMBL22231891 0.76 MPO (0.44) ALDH1A1CYP3A4ALOX15HIF1AHSD17B10
SCHEMBL22232549 0.75 KMT2A (0.42) ALDH1A1CYP3A4MEN1KMT2AMAPT
SCHEMBL7466008 0.75 MEN1 (0.46) MEN1KMT2AMAPTLDHALDHB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843056-A 4-substituted phenylamine derivatives and their use for protecting crops against undesired phytopathogenic microorganisms 印度商皮埃企业有限公司 2019-06-04 CN disclosed