Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 8/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15741057 | 0.86 | CCR5 (0.47) | MEN1MAPTKMT2ACCR5LDHA | |
| SCHEMBL7477576 | 0.82 | PYCR1 (0.41) | MAPTPYCR1KDRCNR2PTGER1 | |
| SCHEMBL7471697 | 0.79 | MEN1 (0.46) | MEN1MAPTKMT2ACNR2 | |
| SCHEMBL7468867 | 0.78 | LDHA (0.43) | PYCR1LDHALDHBPTGER1 | |
| SCHEMBL12782162 | 0.78 | CCR5 (0.47) | MEN1MAPTKMT2ACCR5 | |
| SCHEMBL181115 | 0.76 | KMT2A (0.47) | MEN1MAPTKMT2ACCR5 | |
| SCHEMBL5699805 | 0.76 | ERN1 (0.44) | MEN1MAPTKMT2ACCR5 | |
| SCHEMBL28293841 | 0.75 | ALDH1A1 (0.62) | MEN1MAPTKMT2ALDHALDHB | |
| SCHEMBL11303064 | 0.75 | MAPK1 (0.47) | MEN1MAPTKMT2A | |
| SCHEMBL3890669 | 0.75 | CCR5 (0.54) | MEN1MAPTKMT2ACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757986-B1 | Arylpiperidine and arylpiperazine derivatives and drugs containing the same | SUNTORY LTD (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-5723475-A | Arylpiperidine and arylpiperazine derivatives and medicament containing the same | SUNTORY LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0757986-A1 | ARYLPIPERIDINE AND ARYLPIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |