Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14905976 | 0.84 | CHRM3 (0.36) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL3006812 | 0.84 | CHRM3 (0.36) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL1716907 | 0.84 | CHRM3 (0.36) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| (-)-Methyl Shikimate SCHEMBL15983807 | 0.82 | ALDH1A1 (0.36) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL2829330 | 0.81 | LMNA (0.43) | LMNAMAPTTSHRKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL2829328 | 0.80 | LMNA (0.42) | LMNAMAPTTSHRKMT2AHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL21459005 | 0.79 | OAT (0.33) | GABRR1 | |
| SCHEMBL2828984 | 0.79 | MEN1 (0.42) | LMNAMAPTKMT2AHSD17B10 | |
| SCHEMBL2832851 | 0.77 | GABRR1 (0.44) | GABRR1THRBBLMTSHRKMT2A | |
| SCHEMBL15969897 | 0.74 | CHRM3 (0.30) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791808-B1 | PROCESS FOR THE PREPARATION OF 4,5-DIAMINO SHIKIMICACID | HOFFMANN LA ROCHE (CH) | 2010-07-14 | — | — | EP | disclosed |