Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561002 | 0.79 | RAB9A (0.51) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL31344512 | 0.73 | POLB (0.52) | MAPTRAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL29980877 | 0.73 | NPC1 (0.38) | MAPTRAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL20338487 | 0.73 | NPC1 (0.38) | MAPTRAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL20338490 | 0.72 | CHRNA7 (0.39) | ALDH1A1KDM4ELMNAPOLBCYP1A2 | |
| SCHEMBL19385830 | 0.72 | ALDH1A1 (0.56) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL19385828 | 0.72 | ALDH1A1 (0.56) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL29980210 | 0.71 | MAPT (0.57) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL20338493 | 0.71 | SMN1; SMN2 (0.39) | MAPTRAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL19810722 | 0.71 | MAPT (0.57) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715159-A | Anticancer medicine composition | 国立癌症中心 | 2019-05-03 | — | — | CN | claimed |
| CN-109715607-A | Compounds that inhibit the formation of the C-MYC/MAX/DNA complex | 国立癌症中心 | 2019-05-03 | — | — | CN | claimed |