Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.45 |
| ▸ | KMO | O15229 | 5/20 | 0.44 |
| ▸ | RORB | Q92753 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14754361 | 0.80 | KMO (0.40) | AHRKMORORBIDO1GRM5 | |
| SCHEMBL14754372 | 0.80 | AHR (0.46) | AHRKMORORBNPSR1CYP1B1 | |
| SCHEMBL10280239 | 0.79 | FFAR4 (0.40) | LMNAABL1GRM5GRM1ADORA1 | |
| SCHEMBL14754371 | 0.78 | AHR (0.41) | AHRKMORORBNPSR1CYP1B1 | |
| SCHEMBL14754357 | 0.75 | ABL1 (0.40) | ABL1IDO1 | |
| SCHEMBL13300837 | 0.75 | SMN1; SMN2 (0.40) | LMNANPSR1ABL1IDO1ADORA1 | |
| SCHEMBL14754392 | 0.75 | ADORA1 (0.48) | AHRKMORORBLMNANPSR1 | |
| SCHEMBL14754409 | 0.72 | RORB (0.40) | AHRKMORORBIDO1 | |
| SCHEMBL28494521 | 0.72 | ESR1 (0.39) | ABL1GRM1ADORA1 | |
| SCHEMBL14304002 | 0.72 | PTGS2 (0.40) | ABL1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776537-A | Purinedione as WNT pathway modulators | 新加坡科技研究局 | 2019-05-21 | — | — | CN | disclosed |