SCHEMBL28294088

SCHEMBL28294088

COC1C(=O)Oc2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.42
CYP2C9 P11712 2/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
GAA P10253 3/20 0.39
ATM Q13315 1/20 0.39
ALDH1A1 P00352 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1127602 0.84 MAOA (0.52) KCNA3CYP2C9MAOAMAOBGAA
SCHEMBL7936048 0.79 KCNA3 (0.39) KCNA3CYP2C9MAOAMAOBGAA
SCHEMBL27265304 0.78 KCNA3 (0.47) KCNA3CYP2C9MAOAMAOBGAA
SCHEMBL28198677 0.77 KCNA3 (0.42) KCNA3CYP2C9MAOAMAOBGAA
SCHEMBL10511336 0.75 TDP1 (0.40) KCNA3CYP2C9ALDH1A1
SCHEMBL75199 0.75 CYP2C9 (0.40) CYP2C9MAOAMAOBGAAATM
SCHEMBL18758182 0.75 PKM (0.43) CYP2C9MAOAMAOBGAAATM
SCHEMBL19719097 0.75 KMT2A (0.44) CYP2C9ATMKMT2AMEN1USP2
SCHEMBL29473842 0.74 MAOA (0.45) CYP2C9MAOAMAOBGAAATM
SCHEMBL26185677 0.74 MAOA (0.45) CYP2C9MAOAMAOBGAAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-220194869-U Desolventizing device for synthesizing methoxybenzofuranone 湖北亚金生物科技有限公司 2023-12-19 CN claimed
CN-109775912-B Waste liquid treatment process of methoxybenzofuranone 安徽广信农化股份有限公司 2021-06-29 CN claimed
CN-209322763-U A kind of system of synthesizing methoxy benzofuranone 安徽广信农化股份有限公司 2019-08-30 CN claimed
CN-117645593-A Preparation method of benzofuranone 湖北亚金生物科技有限公司 2024-03-05 CN disclosed
CN-220194869-U Desolventizing device for synthesizing methoxybenzofuranone 湖北亚金生物科技有限公司 2023-12-19 CN disclosed
CN-220194869-U Desolventizing device for synthesizing methoxybenzofuranone 湖北亚金生物科技有限公司 2023-12-19 CN disclosed
CN-220194869-U Desolventizing device for synthesizing methoxybenzofuranone 湖北亚金生物科技有限公司 2023-12-19 CN disclosed
CN-110615775-B Synthetic method of benzofuran-2 (3H) -ketone 湖北斯柏生物科技有限公司 2023-03-24 CN disclosed
CN-215087180-U Novel device for synthesizing benzofuranone by using catalyst 酒泉亚佳化学有限公司 2021-12-10 CN disclosed
CN-215049520-U Be applied to high enriched effluent disposal system of azoxystrobin former pharmaceutical factory 南京合创工程设计有限公司 2021-12-07 CN disclosed
CN-109775912-B Waste liquid treatment process of methoxybenzofuranone 安徽广信农化股份有限公司 2021-06-29 CN disclosed
CN-110615775-A Synthetic method of benzofuran-2 (3H) -ketone 湖北斯柏生物科技有限公司 2019-12-27 CN disclosed
CN-209322763-U A kind of system of synthesizing methoxy benzofuranone 安徽广信农化股份有限公司 2019-08-30 CN disclosed
CN-209322763-U A kind of system of synthesizing methoxy benzofuranone 安徽广信农化股份有限公司 2019-08-30 CN disclosed
CN-209322763-U A kind of system of synthesizing methoxy benzofuranone 安徽广信农化股份有限公司 2019-08-30 CN disclosed
CN-109776326-A A kind of synthesis technology of azoxystrobin intermediate 安徽广信农化股份有限公司 2019-05-21 CN disclosed
CN-109678825-A A kind of synthetic method of Methoxvbenzofuran ketone 安徽广信农化股份有限公司 2019-04-26 CN disclosed
CN-109678825-A A kind of synthetic method of Methoxvbenzofuran ketone 安徽广信农化股份有限公司 2019-04-26 CN disclosed
CN-109651316-A A kind of process for separating and purifying of Methoxvbenzofuran ketone 安徽广信农化股份有限公司 2019-04-19 CN disclosed
CN-109651316-A A kind of process for separating and purifying of Methoxvbenzofuran ketone 安徽广信农化股份有限公司 2019-04-19 CN disclosed