Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28198677 | 0.79 | KCNA3 (0.42) | KCNA3MAOAMAOBGAAATM | |
| SCHEMBL28294088 | 0.79 | KCNA3 (0.42) | KCNA3MAOAMAOBGAAATM | |
| SCHEMBL1127602 | 0.78 | MAOA (0.52) | KCNA3MAOAMAOBGAAATM | |
| SCHEMBL2520386 | 0.66 | KCNA3 (0.44) | KCNA3MAOAMAOBATMKMT2A | |
| SCHEMBL29988174 | 0.65 | MAOA (0.56) | KCNA3MAOAMAOBATMKMT2A | |
| SCHEMBL5344047 | 0.65 | MAOA (0.56) | KCNA3MAOAMAOBATMKMT2A | |
| SCHEMBL3374471 | 0.65 | ATM (0.47) | MAOAMAOBGAAATMKMT2A | |
| SCHEMBL29767372 | 0.65 | MAOA (0.45) | MAOAMAOBGAAATMKMT2A | |
| SCHEMBL5967632 | 0.65 | NR3C1 (0.46) | CYP19A1KMT2ACYP2C9ALDH1A1MAPT | |
| SCHEMBL5730818 | 0.64 | L3MBTL1 (0.50) | MAOAMAOBATMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906265-B1 | CHEMICAL PROCESS | SYNGENTA LTD (GB) | 2001-08-29 | — | — | EP | disclosed |
| US-6048998-A | One-step process for preparing methyl 2-(halomethyl)phenylacetate from 3-isochromanone | ZENECA LIMITED (GB) | 2000-04-11 | — | — | US | disclosed |
| EP-0906265-A1 | CHEMICAL PROCESS | ZENECA LIMITED (GB) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997048671-A1 | CHEMICAL PROCESS | ZENECA LIMITED (GB) | 1997-12-24 | — | — | WO | disclosed |