Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 15/20 | 0.56 |
| ▸ | CA2 | P00918 | 15/20 | 0.56 |
| ▸ | CA12 | O43570 | 13/20 | 0.56 |
| ▸ | CA7 | P43166 | 13/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 13/20 | 0.56 |
| ▸ | CA9 | Q16790 | 8/20 | 0.47 |
| ▸ | PNMT | P11086 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294086 | 0.86 | CA1 (0.39) | CA1CA2CA12CA7CA14 | |
| SCHEMBL27823366 | 0.76 | PNMT (0.40) | PNMT | |
| SCHEMBL28292382 | 0.74 | IDO1 (0.43) | CA1CA2 | |
| SCHEMBL31188987 | 0.73 | CA1 (1.00) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11452177 | 0.73 | CA1 (1.00) | CA1CA2CA12CA7CA14 | |
| SCHEMBL27802706 | 0.71 | HSD17B1 (0.38) | — | |
| SCHEMBL19693671 | 0.68 | CA1 (0.65) | CA1CA2CA12CA7CA14 | |
| SCHEMBL19693718 | 0.67 | CA1 (0.62) | CA1CA2CA12CA7CA14 | |
| SCHEMBL29519375 | 0.67 | CA1 (0.62) | CA1CA2CA12CA7CA14 | |
| SCHEMBL14335118 | 0.65 | CA1 (0.75) | CA1CA2CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109743875-A | The inhibitor of MENIN-MLL interaction | 生命医药公司 | 2019-05-10 | — | — | CN | disclosed |