Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 8/20 | 0.48 |
| ▸ | CHRM3 known ✓ | P20309 | 8/20 | 0.48 |
| ▸ | CHRM2 known ✓ | P08172 | 7/20 | 0.47 |
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188001 | 0.86 | CHRM1 (0.60) | CHRM1CHRM3CHRM5MAPTBLM | |
| Hydrochloric Acid SCHEMBL28722632 | 0.84 | CHRM1 (0.58) | CHRM1CHRM3CHRM5MAPTBLM | |
| SCHEMBL188003 | 0.78 | CHRM1 (0.52) | CHRM1CHRM3CHRM5MAPTBLM | |
| SCHEMBL30378623 | 0.78 | CHRM1 (0.52) | CHRM1CHRM3CHRM5MAPTBLM | |
| SCHEMBL13754776 | 0.78 | CHRM1 (0.75) | CHRM1CHRM3CHRM5MAPTBLM | |
| SCHEMBL20960664 | 0.76 | ADRA2A (0.54) | CHRM1CHRM3CHRM5MAPTBLM | |
| SCHEMBL28041831 | 0.76 | THRB (0.61) | CHRM1CHRM3CHRM5MAPTBLM | |
| Choline SCHEMBL9296180 | 0.75 | CHRM1 (0.47) | CHRM1CHRM3CHRM5MAPTBLM | |
| SCHEMBL15912547 | 0.74 | ADRA2A (0.52) | CHRM1CHRM3CHRM5MAPTBLM | |
| Urea SCHEMBL15993813 | 0.74 | CHRM1 (0.55) | CHRM1CHRM3CHRM5MAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109627148-A | A kind of preparation method of cannabidiol, cannabidiol obtained and application thereof | 中国农业科学院麻类研究所 | 2019-04-16 | — | — | CN | disclosed |