Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21379657 | 0.73 | CNR2 (0.49) | CNR2P2RX7 | |
| SCHEMBL749356 | 0.72 | CNR1 (0.42) | CNR1 | |
| SCHEMBL28292579 | 0.72 | CNR2 (0.50) | CNR2P2RX7CNR1 | |
| SCHEMBL28294346 | 0.69 | CNR2 (0.41) | CNR2 | |
| SCHEMBL30333324 | 0.68 | CNR2 (0.52) | CNR2P2RX7CNR1JAK2JAK1 | |
| SCHEMBL422451 | 0.67 | CNR1 (0.38) | CNR1 | |
| SCHEMBL752887 | 0.66 | CHRM2 (0.44) | CNR1 | |
| SCHEMBL753368 | 0.66 | POLB (0.56) | CNR1 | |
| SCHEMBL15776856 | 0.66 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL13162890 | 0.66 | P2RX7 (0.56) | CNR2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |