Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28940931 | 0.87 | CNR2 (0.40) | CNR2MAOBSCN9ABACE1 | |
| SCHEMBL28292566 | 0.79 | MAOB (0.49) | MAOBSCN9ACNR1 | |
| SCHEMBL21379657 | 0.76 | CNR2 (0.49) | CNR2P2RX7 | |
| SCHEMBL28292577 | 0.73 | CCNC (0.48) | CNR2MAOBSCN9A | |
| SCHEMBL28940932 | 0.72 | CNR2 (0.49) | CNR2MAOBSCN9A | |
| SCHEMBL28940985 | 0.72 | SCN9A (0.44) | MAOBSCN9A | |
| SCHEMBL28292586 | 0.72 | SCN9A (0.44) | MAOBSCN9A | |
| SCHEMBL28294439 | 0.72 | CNR2 (0.49) | CNR2P2RX7CNR1 | |
| SCHEMBL28284688 | 0.71 | CCNC (0.43) | CNR1HRH3 | |
| SCHEMBL28294317 | 0.71 | SCN9A (0.45) | MAOBSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |