Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28848197 | 0.83 | L3MBTL1 (0.43) | ALDH1A1KMT2AMAPT | |
| SCHEMBL28360321 | 0.71 | ALDH1A1 (0.58) | ALDH1A1CYP1A1CYP1B1KMT2ANQO2 | |
| SCHEMBL8214825 | 0.70 | ALDH1A1 (0.41) | ALDH1A1CYP1A1CYP1B1KMT2ANQO2 | |
| SCHEMBL16729562 | 0.69 | CYP24A1 (0.36) | CYP24A1PTGS2 | |
| SCHEMBL16727030 | 0.69 | RXRA (0.36) | CYP24A1KMT2A | |
| SCHEMBL9957932 | 0.69 | ALDH1A1 (0.55) | ALDH1A1CYP1A1CYP1B1NQO2GAA | |
| SCHEMBL9958096 | 0.69 | ALDH1A1 (0.55) | ALDH1A1CYP1A1CYP1B1NQO2GAA | |
| SCHEMBL29066010 | 0.67 | ALDH1A1 (0.52) | ALDH1A1CYP1A1CYP1B1KMT2ANQO2 | |
| SCHEMBL9957670 | 0.65 | ALDH1A1 (0.44) | ALDH1A1CYP1A1CYP1B1NQO2GAA | |
| 1,3,5-Trimethoxybenzene SCHEMBL2496933 | 0.65 | ALDH1A1 (0.65) | ALDH1A1CYP1A1CYP1B1NQO2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379740-B | Novel FGFR3 fusion | 安斯泰来制药株式会社 | 2019-05-14 | — | — | CN | disclosed |