Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283066 | 0.84 | ALDH1A1 (0.71) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL2094345 | 0.82 | ALDH1A1 (0.64) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL3070293 | 0.81 | KDM4E (0.67) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL79802 | 0.81 | KDM4E (1.00) | KDM4EGAAALDH1A1HPGDNPC1 | |
| Hydrogen Sulfide SCHEMBL27471544 | 0.79 | KDM4E (0.96) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL1312094 | 0.79 | TRPV1 (0.74) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL3075908 | 0.79 | ALDH1A1 (0.60) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL9523920 | 0.79 | ALDH1A1 (0.68) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL11291466 | 0.79 | NPC1 (0.79) | KDM4EGAAALDH1A1HPGDNPC1 | |
| SCHEMBL30393282 | 0.79 | KDM4E (0.82) | KDM4EGAAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109642010-A | The synthetic method of poly- Oxazolidinone compound | 科思创德国股份有限公司 | 2019-04-16 | — | — | CN | claimed |