Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | BCR | P11274 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128779 | 0.87 | PTK2 (0.51) | PIK3CDPIK3CGGAATDO2 | |
| SCHEMBL1553208 | 0.86 | PIK3CA (0.65) | PIK3CDPIK3CG | |
| SCHEMBL28118455 | 0.84 | PTK2 (0.54) | PIK3CDPIK3CGGAA | |
| SCHEMBL30338494 | 0.84 | PTK2 (0.57) | PIK3CDPIK3CGGAA | |
| SCHEMBL23193793 | 0.82 | BCL2 (0.48) | KMOLMNAGAAAXL | |
| SCHEMBL29627265 | 0.82 | BCL2 (0.48) | KMOLMNAGAAAXL | |
| SCHEMBL15394357 | 0.80 | RXRA (0.50) | ABL1BCRPIK3CDPIK3CGGAA | |
| SCHEMBL8738131 | 0.80 | KDR (0.55) | ABL1BCRPIK3CDPIK3CGGAA | |
| SCHEMBL31055398 | 0.79 | NAMPT (0.53) | ABL1BCR | |
| SCHEMBL5803994 | 0.78 | ADORA2A (0.50) | ABL1PIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796439-B | Hydroxyproline peptide derivative and preparation method and application thereof | 西安交通大学 | 2020-05-19 | — | — | CN | claimed |
| CN-109796439-A | A kind of hydroxyproline class peptide derivant and its preparation method and application | 西安交通大学 | 2019-05-24 | — | — | CN | claimed |
| CN-109824582-B | Alanine derivative and preparation method and application thereof | 西安交通大学 | 2020-06-19 | — | — | CN | disclosed |
| CN-109796439-B | Hydroxyproline peptide derivative and preparation method and application thereof | 西安交通大学 | 2020-05-19 | — | — | CN | disclosed |
| CN-109824582-A | A kind of alanine derivatives and its preparation method and application | 西安交通大学 | 2019-05-31 | — | — | CN | disclosed |
| CN-109796439-A | A kind of hydroxyproline class peptide derivant and its preparation method and application | 西安交通大学 | 2019-05-24 | — | — | CN | disclosed |