SCHEMBL28118455

SCHEMBL28118455

CC(=O)Nc1ccc(-c2ccc(C(=O)O)cc2)cn1

nearest known ligand 0.72

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 1/20 0.54
HCAR3 P49019 4/20 0.51
CSNK2A2 P19784 1/20 0.50
CSNK2A1 P68400 1/20 0.50
KMT2A Q03164 1/20 0.49
DEGS1 O15121 1/20 0.49
CYP1A2 P05177 1/20 0.49
GAA P10253 1/20 0.49
PIK3CD O00329 1/20 0.48
PIK3CG P48736 1/20 0.48
PARP1 P09874 1/20 0.47
DHODH Q02127 1/20 0.47
DGAT1 O75907 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29128779 0.88 PTK2 (0.51) PTK2HCAR3KMT2ACYP1A2GAA
SCHEMBL30338494 0.87 PTK2 (0.57) PTK2KMT2ADEGS1CYP1A2GAA
SCHEMBL82675 0.86 HCAR3 (0.68) PTK2HCAR3KMT2ACYP1A2GAA
SCHEMBL28294579 0.84 KMO (0.52) GAAPIK3CDPIK3CG
SCHEMBL1552425 0.84 DGAT1 (0.53) DGAT1
SCHEMBL10195598 0.83 PTK2 (0.57) PTK2KMT2ACYP1A2GAAPIK3CD
SCHEMBL27995832 0.83 KDR (0.57) HCAR3DEGS1CYP1A2DGAT1
SCHEMBL30422958 0.83 CSNK2A1 (0.51) PTK2CSNK2A1CYP1A2GAAPIK3CD
SCHEMBL22575346 0.83 CSNK2A1 (0.51) PTK2CSNK2A1CYP1A2GAAPIK3CD
SCHEMBL5543076 0.80 BCL2 (0.52) HCAR3DEGS1DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824581-B Alanine-containing peptide-like compound and preparation method and application thereof 西安交通大学 2020-08-18 CN disclosed
CN-109824584-B Tertiary leucine-containing peptoid compound and preparation method and application thereof 西安交通大学 2020-08-18 CN disclosed
CN-109734660-B Tert-butyl substituted serine-containing peptide-like compound and preparation method and application thereof 西安交通大学 2020-07-28 CN disclosed
CN-109651243-B Serine-containing peptoid compound and preparation method and application thereof 西安交通大学 2020-05-22 CN disclosed
CN-109761957-B Hydroxyproline-containing compound and preparation method and application thereof 西安交通大学 2020-05-19 CN disclosed
CN-109796439-B Hydroxyproline peptide derivative and preparation method and application thereof 西安交通大学 2020-05-19 CN disclosed
CN-109824581-A A kind of class peptides containing alanine with and its preparation method and application 西安交通大学 2019-05-31 CN disclosed
CN-109824584-A A kind of class peptides and its preparation method and application containing Terleu 西安交通大学 2019-05-31 CN disclosed
CN-109796439-A A kind of hydroxyproline class peptide derivant and its preparation method and application 西安交通大学 2019-05-24 CN disclosed
CN-109761957-A A kind of compound and its preparation method and application containing hydroxyproline 西安交通大学 2019-05-17 CN disclosed
CN-109734660-A A kind of class peptides of serine and its preparation method and application replaced containing tert-butyl 西安交通大学 2019-05-10 CN disclosed
CN-109651243-A A kind of class peptides and its preparation method and application containing serine 西安交通大学 2019-04-19 CN disclosed
CN-104262244-B A kind of 5-phenylpyridine-2-amine Bcr-Abl inhibitor and its preparation method and application Xi''an Jiao Tong University (CN) 2017-01-04 CN disclosed