Methylamine

Methylamine

SCHEMBL28294591

CC(C)(C)c1ccc(C(C)(C)C)cc1.CN

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.65
LMNA P02545 1/20 0.61
TYR P14679 1/20 0.61
ALDH1A1 P00352 5/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
MAPT P10636 2/20 0.52
HPGD P15428 2/20 0.52
MAPK1 P28482 1/20 0.52
SLC22A2 O15244 1/20 0.52
SLC22A1 O15245 1/20 0.52
SLC22A3 O75751 1/20 0.52
KIF11 P52732 2/20 0.50
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
MEN1 O00255 1/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
RECQL P46063 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL424728 0.92 TSHR (0.73) TSHRLMNATYRALDH1A1NPC1
SCHEMBL8889645 0.83 TSHR (0.55) TSHRLMNATYRALDH1A1NPC1
SCHEMBL33319 0.83 RAB9A (0.73) TSHRLMNATYRALDH1A1NPC1
SCHEMBL17923896 0.81 TSHR (0.61) TSHRLMNATYRALDH1A1NPC1
SCHEMBL26915 0.81 KIF11 (0.70) TSHRLMNATYRALDH1A1NPC1
SCHEMBL1538330 0.81 TSHR (0.61) TSHRLMNATYRALDH1A1NPC1
SCHEMBL3423876 0.81 KIF11 (0.70) TSHRLMNATYRALDH1A1NPC1
Hydrochloric Acid SCHEMBL2864451 0.81 RAB9A (0.70) TSHRLMNATYRALDH1A1NPC1
SCHEMBL5495871 0.79 TSHR (1.00) TSHRLMNATYRALDH1A1NPC1
SCHEMBL1931781 0.79 KIF11 (0.67) TSHRLMNATYRALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109666166-A A kind of energy-absorbing method based on dynamic crosslinking polymer 翁秋梅 2019-04-23 CN disclosed