Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707145 | 0.85 | MEN1 (0.57) | TDP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28448195 | 0.85 | MEN1 (0.57) | TDP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28408346 | 0.85 | MEN1 (0.45) | THRBTDP1MEN1KMT2ANPC1 | |
| SCHEMBL4853047 | 0.82 | NPC1 (0.61) | TDP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15615056 | 0.79 | MEN1 (0.51) | TDP1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL393417 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2154879 | 0.78 | NPC1 (0.52) | TDP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20053034 | 0.78 | MEN1 (0.57) | TDP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4862311 | 0.78 | RAB9A (0.61) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23332259 | 0.78 | NPC1 (0.52) | TDP1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796372-A | A method of preparing polysubstituted alkenyl amidine | 中国科学院化学研究所 | 2019-05-24 | — | — | CN | disclosed |